Posts Tagged
‘migration’

September 1, 2021

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by: admin

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Tags: Autism, inhibitor, migration, model, neuronal, normalizes, organoid, Protein, Spectrum

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Categories: autism

On the move: Neurons from month-old organoids with 16p11.2 deletions (right) migrate more slowly than those from control organoids (left). Inhibiting a protein that helps cells move or change shape prevents atypical neural migration in 3D clusters of brain cells that carry genetic variants associated with autism, according to a new study. The cell models […]

June 24, 2021

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by: admin

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Tags: Autismlinked, brain, cell, disrupt, migration, mutation, Spectrum

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Categories: autism

Disorganized scaffolds: Immature brain cells from mutant CUL3 mice have a disordered cytoskeleton (right) compared to controls (left). Mutations in CUL3, a leading autism gene, can disrupt the movement of neurons during development and disrupt the precise assembly of the brain, suggests a new study. Correcting this misdirection could lead to therapy for autism in […]